THE BASIC PRINCIPLES OF LDN-27219 CANCER TREATMENT RESEARCH

One particular notably intriguing compound is LDN-27219. Whilst most tTG inhibitors are meant to bind to your protein crosslinking active web page, LDN-27219 in its place binds on the nucleotide binding pocket from the enzyme while it truly is in its closed-condition conformation, and stabilizes that conformation to prevent crosslinking activity.78